Abstract: Purpose: Polymyositis (PM) is an inflammatory muscle disease, which has more overlap with scleroderma than other connective tissue diseases. The aim of this study is to compare the clinical, paraclinical and therapeutic response of polymyositis with polymyositis-scleroderma overlap syndrome. Methods: During the past 10 years we had 16 overlap syndromes and 40 primary polymyositis. All patients were classified by the American college of Rheumatology classification criteria. Ninety-seven items were checked in ...
Abstract: Introduction: The association of Behcet’s disease (BD) and Ankylosing Spondylitis (AS) is still a controversial subject. As the presence of sacroiliac joint (SIJ) involvement is an essential criterion in the diagnosis of AS, we decided to determine the prevalence of SIJ involvement in BD and compare it with control group. Materials & Methods: We selected randomly 199 BD patients and 168 non-BD cases (CG), in a 12 month period (between April ...
Abstract: Objective: Systemic sclerosis is a generalized disorder of connective tissue disease. This study surveyed the clinical manifestations of systemic sclerosis in early (6 years) phases of limited and diffuse variants. Methods: Nineteen patients with diffuse and thirty-four cases with limited form of disease were selected consecutively from 1992 to 1998. Sixty-five clinical data were evaluated and then analyzed by MC-Nemar chi square test between two forms in both phases. Results: (1) There were ...
Abstract: The neuropsychiatric manifestations of systemic lupus erythematosus are frequent. One of the most serious presentations is convulsion. This study was carried out to evaluate the relation between convulsion and anti-DNA antibody levels. An analytic, retrospective case-controlled study was carried out, with reference to 1001 recorded cases of systemic SLE lupus erythematosus in Lupus Unit, Rheumatology Center, Shariati Hospital, Tehran University of Medical Sciences. The frequency Of convulsion was 13.3%. There ...
Abstract: Introduction: Ocular lesions of Behcet’s Disease (BD) need aggressive treatment to prevent from severe loss of vision or blindness. Although cytotoxic drugs are thought to be the main therapeutic arsenal, no control study has yet been done to demonstrate their efficacy. This study was designed t evaluate the short-term efficacy of pulse cyclophosphamide in a randomized double blind control study. Materials & Methods: PCP was used as Ig per square meter ...
Abstract: Objective: To assess the course of maternal disease and outcome of pregnancy in patients with systemic lupus erythematosus (SLE). Patients and Methods: One hundred SLE patients who carried out 128 pregnancies were studied retrospectively. These patients were followed in lupus unit every one to two months by the rheumatologist and obstetrician team throughout pregnancy. Some patients were given prophylactic low-dose Prednisolone. Lupus flares were treated by increasing Prednisolone doses. Patients who ...
Abstract: Objective: Exercises, especially sports have an effective role in increasing of Bone Mineral Density (BMD). This study surveyed the bone density in athlete women compared to Iranian standard BMD at the same age and sex. Methods: This study was a prospective survey on thirty-nine athlete women between 20 to 30 years old. Subjects were selected randomly in six different athletes groups including basketball, volleyball, tennis, badminton, swimming and running. BMD was measured ...
Abstract: INTRODUCTION: There are six sets of diagnosis criteria for Behcet's Disease (BD). There is yet no general agreement on which one to use. The International criteria was created to bring this agreement. The aim of this study was to evaluate these criteria, especially the performance of the International criteria. MATERIALS and METHODS: Three countries (China, Iran and Korea) participated in the study. In each country, BD patients were selected as every ...
Abstract: Introduction: Posterior uveitis (PU) and retinal vasculitis (RV) are the main morbidity factor in Behcet’s Disease (BD). They usually progress toward severe loss of vision or blindness. They need aggressive treatment with cytotoxic drugs. Azathioprine was demonstrated, in a double blind control study, to be effective in Behcet’s Disease. The aim of this study was to evaluate the efficacy of Azathioprine in ocular lesions of BD, and to compare ...
Abstract: The bone mass density (BMD) may vary in different countries due to different genetic and environmental factors. This study was performed to determine the BMD of the normal population in Iran. Subjects were selected randomly from different social workers classes in Tehran (from the lowest to the highest). For each decade and sexes, 20 normal subjects were selected (140 men and 140 women). BMD was measured with a Hologic 1000 ...